Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13259166 | 0.80 | MEN1 (0.48) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL6893301 | 0.78 | CYP4F2 (0.46) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL15551008 | 0.78 | MMP8 (0.43) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL16841345 | 0.76 | MEN1 (0.37) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL3963660 | 0.76 | MEN1 (0.44) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL13259175 | 0.73 | MEN1 (0.42) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL9978375 | 0.72 | PKM (0.62) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL24425847 | 0.70 | MEN1 (0.40) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL5613290 | 0.69 | — | — | |
| SCHEMBL12659666 | 0.69 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179427-A1 | METHODS FOR PRODUCING BERAPROST AND ITS DERIVATIVES | LUNG BIOTECHNOLOGY PBC (US) | 2015-11-26 | — | — | WO | disclosed |