Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388276 | 0.77 | KDM4E (0.59) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL30205255 | 0.77 | KDM4E (0.59) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL3478941 | 0.76 | CHRNB2 (0.45) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL8265473 | 0.76 | CHRNB2 (0.45) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL13041691 | 0.76 | ALDH1A1 (0.59) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL111276 | 0.74 | RAB9A (0.66) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL29391888 | 0.74 | RAB9A (0.66) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL12213872 | 0.74 | MAPT (0.68) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL17702672 | 0.74 | CHRNB2 (0.43) | RAB9ASMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL8265318 | 0.74 | MAPT (0.46) | POLBALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150336959-A1 | Electronic Device | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336959-A1 | Electronic Device | ETFB, ETFA, XPOT | RAB9A 2505/4885SMN1; SMN2 2933/4885POLB 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.