Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306866 | 0.87 | SLC6A2 (0.55) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27509973 | 0.85 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3HDAC1HDAC8 | |
| SCHEMBL23527429 | 0.85 | CHRNB2 (0.58) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2838545 | 0.82 | ALDH1A1 (0.56) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29000147 | 0.79 | LMNA (0.43) | SLC6A2SLC6A4SLC6A3HDAC1HDAC8 | |
| SCHEMBL17209157 | 0.79 | ALDH1A1 (0.60) | SLC6A4ALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL14067584 | 0.79 | ALDH1A1 (0.60) | SLC6A4ALDH1A1CYP3A4CA12CA1 | |
| Biphenyl SCHEMBL7785984 | 0.79 | ALDH1A1 (0.60) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL320180 | 0.79 | ALDH1A1 (0.60) | SLC6A4ALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL2956444 | 0.79 | SLC6A2 (0.63) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521125-B1 | Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |