Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | ACP3 | P15309 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23527429 | 0.97 | CHRNB2 (0.58) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL2838545 | 0.94 | ALDH1A1 (0.56) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| Biphenyl SCHEMBL7785984 | 0.90 | ALDH1A1 (0.60) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL2956444 | 0.90 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL172870 | 0.87 | CHRNB2 (0.45) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL22238270 | 0.87 | MMP3 (0.64) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL3045847 | 0.87 | MMP3 (0.64) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL22388390 | 0.87 | CYP1A2 (0.64) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL144 | 0.87 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL27907795 | 0.87 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324604-A | Multi-active electrophotographic element and imaging process using free radicals as charge transport material | EASTMAN KODAK COMPANY (US) | 1994-06-28 | — | — | US | claimed |
| EP-3475995-B1 | QUANTUM DOT LIGHT EMITTING DEVICES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-12-21 | — | — | EP | disclosed |
| US-5324604-A | Multi-active electrophotographic element and imaging process using free radicals as charge transport material | EASTMAN KODAK COMPANY (US) | 1994-06-28 | — | — | US | disclosed |