SCHEMBL510022

SCHEMBL510022

Cc1cc(-c2ccc(-c3ccc(O)cc3)cc2)cc(-c2ccccc2)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.55
MMP3 P08254 1/20 0.54
BCL2L1 Q07817 1/20 0.54
PTPN1 P18031 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
USP7 Q93009 1/20 0.49
POLB P06746 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
BACE1 P56817 2/20 0.47
ALOX5 P09917 1/20 0.46
ESR1 P03372 3/20 0.45
PDE4A P27815 1/20 0.45
PDE4B Q07343 1/20 0.45
PDE4C Q08493 1/20 0.45
PDE4D Q08499 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ABL1 P00519 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31028131 0.91 CA1 (0.54) ESR2BCL2L1PTPN1HTTBACE1
SCHEMBL172874 0.91 CA1 (0.54) ESR2BCL2L1PTPN1HTTBACE1
SCHEMBL3810063 0.87 MMP3 (0.65) ESR2MMP3BCL2L1PTPN1MEN1
SCHEMBL28612538 0.81 ESR2 (0.58) ESR2MMP3BCL2L1MEN1KMT2A
SCHEMBL2861284 0.81 ESR2 (0.62) ESR2BCL2L1PTPN1MEN1KMT2A
SCHEMBL17220670 0.80 CA1 (0.70) ESR2MMP3BCL2L1MEN1KMT2A
SCHEMBL278774 0.80 CA1 (0.70) ESR2MMP3BCL2L1MEN1KMT2A
SCHEMBL411275 0.80 CA1 (0.70) ESR2MMP3BCL2L1PTPN1HTT
SCHEMBL503537 0.80 CA1 (0.70) ESR2MMP3BCL2L1MEN1KMT2A
Phenol SCHEMBL7039341 0.78 CA1 (0.67) ESR2MMP3BCL2L1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524467-B Containing ester group tetracarboxylic acid dianhydride, polyester-imide precursor, polyester-imide and manufacture method thereof HONSHU CHEMICAL IND (JP) 2015-10-28 CN disclosed
US-9096566-B2 Ester group-containing tetracarboxylic acid dianhydride, polyester polyimide precursor, polyesterimide, and methods for producing same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2015-08-04 US disclosed
CN-102234256-B Novel diepoxide HONSHU CHEMICAL IND 2014-12-10 CN disclosed
CN-103524467-A Ester group-containing tetracarboxylic dianhydride, polyimide precursor polyester, polyester imide and its manufacturing method HONSHU CHEMICAL IND 2014-01-22 CN disclosed
US-20120029164-A1 ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-02-02 US disclosed
CN-102234256-A Novel diepoxide HONSHU CHEMICAL IND 2011-11-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029164-A1 ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME ALK, ALKBH3, IGLV6-57 ESR2 3051/4885MMP3 4755/4885BCL2L1 3830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.