Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133381 | 0.81 | ALDH1A1 (0.54) | ADRA2CKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7924167 | 0.81 | KCNH2 (0.67) | BCL2A1ADRA2CKCNH2ALDH1A1KDM4E | |
| SCHEMBL12534408 | 0.80 | ALDH1A1 (0.44) | DRD2DRD3ADRA2CKCNH2KMT2A | |
| SCHEMBL8256209 | 0.79 | DRD2 (0.59) | DRD2DRD3KCNH2KMT2AMEN1 | |
| SCHEMBL14733342 | 0.78 | KMT2A (0.51) | DRD2DRD3ADRA2CKCNH2KMT2A | |
| SCHEMBL12879707 | 0.76 | L3MBTL1 (0.51) | DRD2DRD3BCL2A1MAPTHSD17B10 | |
| SCHEMBL17144424 | 0.75 | KCNH2 (0.59) | BCL2A1ADRA2CKCNH2ALDH1A1MAPT | |
| SCHEMBL25575682 | 0.75 | L3MBTL1 (0.54) | DRD2DRD3ALDH1A1KDM4EMAPT | |
| SCHEMBL24061151 | 0.74 | MAPKAPK2 (0.58) | ADRA2CKCNH2KMT2AALDH1A1KDM4E | |
| SCHEMBL13006962 | 0.74 | ALDH1A1 (0.56) | DRD2DRD3KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542667-B1 | UREIDO SUBSTITUTED BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE | PTC THERAPEUTICS INC (US) | 2012-03-07 | — | — | EP | disclosed |