Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728435 | 0.92 | SIRT2 (0.50) | ENPP1SIRT2SIRT1SIRT3ACHE | |
| SCHEMBL3266987 | 0.85 | ENPP1 (0.45) | ENPP1SIRT2SIRT1SIRT3ACHE | |
| SCHEMBL1730265 | 0.85 | SIRT2 (0.50) | SIRT2SIRT1SIRT3CHRM4MAOB | |
| SCHEMBL1728813 | 0.82 | SIRT2 (0.51) | SIRT2SIRT1SIRT3ACHEDRD2 | |
| SCHEMBL1728789 | 0.82 | ENPP1 (0.46) | ENPP1ACHEDRD2DRD4 | |
| SCHEMBL1728885 | 0.80 | CHRM4 (0.53) | ENPP1ACHECHRM4BCHE | |
| SCHEMBL1729234 | 0.80 | ENPP1 (0.42) | ENPP1SIRT2SIRT1SIRT3ACHE | |
| SCHEMBL1729968 | 0.79 | HRH3 (0.58) | ENPP1ACHECHRM4BCHE | |
| SCHEMBL3265661 | 0.79 | SIRT2 (0.49) | ENPP1SIRT2SIRT1SIRT3ACHE | |
| SCHEMBL5752154 | 0.78 | CHRM4 (0.45) | ENPP1SIRT2SIRT1SIRT3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |