Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081546 | 0.88 | HRH3 (0.42) | HRH3MCHR1 | |
| SCHEMBL1727559 | 0.86 | HRH3 (0.51) | HRH3 | |
| SCHEMBL1727579 | 0.84 | SIGMAR1 (0.52) | HRH3MCHR1 | |
| SCHEMBL1729757 | 0.83 | LTA4H (0.53) | LTA4HHRH3HRH2HRH1MCHR1 | |
| SCHEMBL1727689 | 0.82 | HRH3 (0.48) | HRH3MCHR1 | |
| SCHEMBL1728856 | 0.82 | HRH3 (0.42) | HRH3MCHR1 | |
| SCHEMBL1728687 | 0.82 | HRH3 (0.39) | HRH3MCHR1 | |
| SCHEMBL1728688 | 0.81 | LSS (0.48) | LTA4HHRH3MCHR1 | |
| SCHEMBL1728644 | 0.81 | HRH3 (0.42) | HRH3MCHR1 | |
| SCHEMBL1727343 | 0.81 | PDE6D (0.46) | HRH3MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551810-B1 | DIARYL-SUBSTITUTED CYCLIC UREA DERIVATIVES HAVING AN MCH-MODULATORY EFFECT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-11-30 | — | — | EP | disclosed |