Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | ACACA | Q13085 | 5/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730192 | 0.89 | CKS1B (0.46) | ACACBACACAPDE10AMAPTCKS1B | |
| SCHEMBL1728164 | 0.89 | KDM4E (0.45) | MAP4K4ACACBACACAPDE10AKCNH2 | |
| SCHEMBL1727898 | 0.85 | ACACB (0.40) | MAP4K4ACACBACACAMAPTKCNH2 | |
| SCHEMBL1727922 | 0.84 | DRD2 (0.46) | — | |
| SCHEMBL1727890 | 0.84 | HTR1A (0.40) | MAP4K4SMOACACBACACAPDE10A | |
| SCHEMBL1727647 | 0.84 | MAP4K4 (0.40) | MAP4K4ACACBACACAPDE10AMAPT | |
| SCHEMBL1729306 | 0.83 | HRH3 (0.46) | MAP4K4SMOACACBACACAPDE10A | |
| SCHEMBL1727727 | 0.82 | MAP4K4 (0.40) | MAP4K4ACACBCKS1BSKP1SKP2 | |
| SCHEMBL1728923 | 0.82 | HRH3 (0.49) | MAP4K4ACACBACACAMAPT | |
| SCHEMBL1728683 | 0.82 | DRD3 (0.40) | MAP4K4ACACBACACAPDE10AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |