Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 12/20 | 0.46 |
| ▸ | SKP1 | P63208 | 12/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 12/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728883 | 0.89 | MAP4K4 (0.44) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL1728164 | 0.88 | KDM4E (0.45) | HCAR2ACACBACACAHTR3AHRH4 | |
| SCHEMBL1729037 | 0.87 | HCAR2 (0.46) | CKS1BSKP1SKP2HCAR2ACACB | |
| SCHEMBL1730124 | 0.86 | CHRM4 (0.46) | CKS1BSKP1SKP2HTR3A | |
| SCHEMBL1729260 | 0.85 | HTR3A (0.42) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL1727922 | 0.84 | DRD2 (0.46) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1727890 | 0.82 | HTR1A (0.40) | ACACBACACAMAPTPDE10A | |
| SCHEMBL1727647 | 0.82 | MAP4K4 (0.40) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL1727727 | 0.82 | MAP4K4 (0.40) | CKS1BSKP1SKP2ACACB | |
| SCHEMBL1728683 | 0.81 | DRD3 (0.40) | CKS1BSKP1SKP2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |