Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729688 | 0.91 | LMNA (0.59) | LMNAKDM4EABL1CHRM4MEN1 | |
| SCHEMBL1730318 | 0.84 | HRH3 (0.43) | LMNAKDM4EABL1KMT2ASMN1; SMN2 | |
| SCHEMBL1727687 | 0.84 | PDE10A (0.43) | LMNAKDM4EABL1CHRM4KMT2A | |
| SCHEMBL1728906 | 0.84 | DEGS1 (0.48) | LMNAKDM4EABL1SMN1; SMN2MAPT | |
| SCHEMBL1727662 | 0.82 | HTR1A (0.43) | LMNAKDM4EABL1CHRM4 | |
| SCHEMBL30286305 | 0.82 | KDM4E (0.71) | LMNAKDM4EABL1CHRM4MEN1 | |
| SCHEMBL1729359 | 0.82 | KDM1A (0.45) | LMNAALDH1A1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL1729679 | 0.81 | CHRM4 (0.48) | CHRM4CHRM2CHRM1DPP4JAK2 | |
| SCHEMBL3783822 | 0.81 | KDM4E (0.57) | LMNAKDM4EABL1CHRM4MEN1 | |
| SCHEMBL30286061 | 0.79 | KDM4E (0.65) | LMNAKDM4EABL1CHRM4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |