Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265528 | 0.84 | HDAC6 (0.47) | PKMHDAC6KDM4EKMT2ASLC6A7 | |
| SCHEMBL2359980 | 0.80 | CHRM4 (0.61) | PKMHDAC6KDM4EKMT2ASLC6A7 | |
| SCHEMBL16480406 | 0.80 | HDAC6 (0.51) | PKMHDAC6KDM4ESLC6A7CHRM4 | |
| SCHEMBL1729003 | 0.79 | PKM (0.48) | PKMHDAC6KDM4EKMT2ASLC6A7 | |
| SCHEMBL9893124 | 0.78 | HDAC6 (0.52) | PKMHDAC6KDM4ESLC6A7CHRM4 | |
| SCHEMBL9891899 | 0.78 | DRD2 (0.58) | PKMHDAC6SLC6A7CHRM4HTR1A | |
| SCHEMBL2324834 | 0.78 | CHRM4 (0.68) | PKMHDAC6KDM4EKMT2ASLC6A7 | |
| SCHEMBL3986386 | 0.78 | ADRB1 (0.58) | PKMHDAC6KDM4EKMT2ASLC6A7 | |
| SCHEMBL2326691 | 0.76 | ADRB1 (0.48) | PKMHDAC6KDM4EKMT2ASLC6A7 | |
| SCHEMBL28070992 | 0.76 | ADRB1 (0.73) | PKMHDAC6KDM4EKMT2ASLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |