SCHEMBL17293201

SCHEMBL17293201

O=C(O)[C@](Cl)(C(Cl)c1ccccc1)N(Cl)Cl

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
LMNA P02545 4/20 0.38
CYP2D6 P10635 1/20 0.38
SRC P12931 1/20 0.38
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTT P42858 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29167283 1.00 CYP1A2 (0.39) CYP1A2LMNACYP2D6SRCTSHR
SCHEMBL10884348 0.78 ESR1 (0.40)
SCHEMBL5152961 0.76 CYP1A2 (0.45) CYP1A2LMNACYP2D6SRCTSHR
SCHEMBL27690229 0.76 MMP8 (0.43) CYP1A2LMNACYP2D6TSHRL3MBTL1
SCHEMBL29141154 0.73 CYP1A2 (0.42) CYP1A2LMNACYP2D6SRCTSHR
SCHEMBL10690917 0.73 CYP1A2 (0.42) CYP1A2LMNACYP2D6SRCTSHR
SCHEMBL8525796 0.70 TSHR (0.55) LMNACYP2D6SRCTSHRMAPK1
SCHEMBL9435845 0.69 TSHR (0.38) CYP1A2LMNACYP2D6SRCTSHR
SCHEMBL6533418 0.68 CYP2C19 (0.44) CYP1A2LMNACYP2D6SRCTSHR
SCHEMBL11616150 0.67 LMNA (0.38) CYP1A2LMNACYP2D6SRCTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117625666-A Construction method and application of pasteurella multocida resistance marker gene-free integrated strain 华南农业大学 2024-03-01 CN claimed
EP-3149029-B1 LIPIDATED PEPTIDES AS NEUROPROTECTIVE AGENTS USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2019-06-19 EP claimed
EP-3094643-B1 LIPIDATED PEPTIDES FOR LOWERING BLOOD GLUCOSE FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY V V I (CZ) 2018-10-17 EP claimed
EP-3149029-A1 LIPIDATED PEPTIDES AS NEUROPROTECTIVE AGENTS Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) 2017-04-05 EP claimed
US-20170051031-A1 LIPIDATED PEPTIDES AS NEUROPROTECTIVE AGENTS USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2017-02-23 US claimed
WO-2015180698-A1 LIPIDATED PEPTIDES AS NEUROPROTECTIVE AGENTS USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2015-12-03 WO claimed
CN-117625666-A Construction method and application of pasteurella multocida resistance marker gene-free integrated strain 华南农业大学 2024-03-01 CN disclosed
CN-117625666-A Construction method and application of pasteurella multocida resistance marker gene-free integrated strain 华南农业大学 2024-03-01 CN disclosed
US-10751390-B2 Lipidated peptides as neuroprotective agents USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2020-08-25 US disclosed
EP-3149029-B1 LIPIDATED PEPTIDES AS NEUROPROTECTIVE AGENTS USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2019-06-19 EP disclosed
US-20170051031-A1 LIPIDATED PEPTIDES AS NEUROPROTECTIVE AGENTS USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2017-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10751390-B2 Lipidated peptides as neuroprotective agents GABARAPL1, GABARAP, GABARAPL2 CYP1A2 4849/4885LMNA 3447/4885CYP2D6 4823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.