Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | ELANE | P08246 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849360 | 0.86 | ELANE (0.56) | ALDH1A1SMN1; SMN2ELANENPC1RAB9A | |
| SCHEMBL11792659 | 0.85 | MAOA (0.53) | ALDH1A1SMN1; SMN2ELANENPC1RAB9A | |
| SCHEMBL28256775 | 0.81 | ELANE (0.55) | ALDH1A1SMN1; SMN2ELANENPC1RAB9A | |
| SCHEMBL1053183 | 0.79 | ELANE (0.56) | ALDH1A1SMN1; SMN2ELANENPC1RAB9A | |
| SCHEMBL28243913 | 0.78 | PTPN1 (0.48) | ALDH1A1SMN1; SMN2ELANENPC1RAB9A | |
| Anthraquinone SCHEMBL27877074 | 0.78 | ELANE (0.56) | ALDH1A1SMN1; SMN2ELANERAB9AMAPK1 | |
| SCHEMBL30389447 | 0.78 | ELANE (0.56) | ALDH1A1SMN1; SMN2ELANERAB9AMAPK1 | |
| SCHEMBL486105 | 0.78 | ELANE (0.56) | ALDH1A1SMN1; SMN2ELANERAB9AMAPK1 | |
| Anthraquinone SCHEMBL27601272 | 0.77 | MEN1 (0.63) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL2384212 | 0.76 | PTPN1 (0.47) | ALDH1A1SMN1; SMN2ELANENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660918-B | Preparation of 2, 6-and 2, 7-disubstituted anthraquinone derivatives | 巴斯夫欧洲公司 | 2019-10-11 | — | — | CN | disclosed |
| US-10227281-B2 | Preparation of 2,6- and 2,7-disubstituted anthraquinone derivates | BASF SE (DE) | 2019-03-12 | — | — | US | disclosed |
| US-20180215694-A1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-9988268-B2 | Preparation of 2,6- and 2,7-disubstituted anthraquinone derivatives | BASF SE (DE) | 2018-06-05 | — | — | US | disclosed |
| EP-3148928-B1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATIVES | BASF SE (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-3148927-B1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATES | BASF SE (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-20170197830-A1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATIVES | BASF SE (DE) | 2017-07-13 | — | — | US | disclosed |
| CN-106660918-A | preparation of 2, 6-and 2, 7-disubstituted anthraquinone derivatives | 巴斯夫欧洲公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-3148928-A1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATIVES | BASF SE (DE) | 2017-04-05 | — | — | EP | disclosed |
| EP-3148927-A1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATES | BASF SE (DE) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181297-A1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATIVES | BASF SE (DE) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015181283-A1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATES | BASF SE (DE) | 2015-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197830-A1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATIVES | ANTXR2, NQO1, DHPS | ALDH1A1 458/4885SMN1; SMN2 4589/4885ELANE 672/4885 |
| US-20180215694-A1 | PREPARATION OF 2,6- AND 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATES | NQO1, CYP1B1, SDHA | ALDH1A1 162/4885SMN1; SMN2 649/4885ELANE 1381/4885 |
| US-10227281-B2 | Preparation of 2,6- and 2,7-disubstituted anthraquinone derivates | NQO1, CYP1B1, SDHA | ALDH1A1 162/4885SMN1; SMN2 649/4885ELANE 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.