Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686071 | 1.00 | ADRA2A (0.44) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL26558297 | 0.84 | KMT2A (0.39) | ADRA2AADRA2CKMT2ATAAR1THRB | |
| SCHEMBL28101855 | 0.78 | CHRM2 (0.41) | LMNAALDH1A1KMT2ATAAR1THRB | |
| SCHEMBL2736669 | 0.77 | CHRM2 (0.35) | LMNAALDH1A1KMT2ATAAR1THRB | |
| SCHEMBL2736667 | 0.77 | CHRM2 (0.35) | LMNAALDH1A1KMT2ATAAR1THRB | |
| SCHEMBL959684 | 0.75 | DPP4 (0.44) | ADRA2AADRA2CDPP4F2KMT2A | |
| SCHEMBL18257694 | 0.75 | THRB (0.53) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL15181483 | 0.75 | DPP4 (0.44) | ADRA2AADRA2CDPP4F2KMT2A | |
| SCHEMBL96936 | 0.75 | HCAR2 (0.47) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL12262583 | 0.75 | THRB (0.53) | ADRA2AADRA2CLMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3149024-A1 | DERIVATIVES OF DOLAPROINE-DOLAISOLEUINE PEPTIDES | Agensys, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015183978-A1 | DERIVATIVES OF DOLAPROINE-DOLAISOLEUINE PEPTIDES | AGENSYS, INC. (US) | 2015-12-03 | — | — | WO | disclosed |