Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836186 | 0.86 | L3MBTL1 (0.68) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL25009812 | 0.85 | L3MBTL1 (0.76) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL30556174 | 0.85 | L3MBTL1 (0.76) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL14741028 | 0.84 | LMNA (0.66) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL17978281 | 0.84 | KMT2A (0.66) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL15544944 | 0.83 | L3MBTL1 (0.73) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| Ethyl Nicotinate SCHEMBL8164637 | 0.82 | L3MBTL1 (0.71) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL21243071 | 0.82 | LMNA (0.82) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL837646 | 0.82 | LMNA (0.64) | KMT2ALMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL25009811 | 0.82 | L3MBTL1 (0.82) | KMT2ALMNATDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107298653-B | A method of synthesis 4- trifluoromethyl nicotinic acid | 江苏建农植物保护有限公司 | 2019-05-17 | — | — | CN | disclosed |
| EP-3148975-A1 | NOVEL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2017-04-05 | — | — | EP | disclosed |
| CN-105358151-A | Compounds for treating spinal muscular atrophy | HOFFMANN LA ROCHE | 2016-02-24 | — | — | CN | disclosed |
| WO-2015180612-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-12-03 | — | — | WO | disclosed |
| CN-101888999-B | Pyridylmethyl-sulfonamide compounds | BASF SE | 2013-12-11 | — | — | CN | disclosed |