Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 10/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27614055 | 0.88 | TGFBR1 (0.54) | KDM4EPKMTGFBR1CETP | |
| SCHEMBL6582812 | 0.85 | CA12 (0.56) | USP30CYP2D6HSD17B10 | |
| SCHEMBL377671 | 0.81 | ALDH1A1 (0.58) | KDM4ECYP2D6HSD17B10 | |
| SCHEMBL18987045 | 0.80 | USP30 (0.62) | BRD4KDM4EPKMTGFBR1USP30 | |
| SCHEMBL6583644 | 0.79 | CYP2D6 (0.48) | USP30CYP2D6HSD17B10 | |
| SCHEMBL27614053 | 0.79 | KDM4E (0.50) | KDM4EPKMTGFBR1CETP | |
| SCHEMBL6397967 | 0.79 | MGLL (0.64) | KDM4EPKMCCR3CETP | |
| SCHEMBL3249543 | 0.78 | MGLL (0.57) | — | |
| SCHEMBL14255786 | 0.77 | GPR119 (0.57) | KDM4EPKMTGFBR1CETP | |
| SCHEMBL331605 | 0.77 | ALDH1A1 (0.51) | USP30CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184222-A1 | INHIBITORS OF HEPATOCYTE GROWTH FACTOR [HGF] AND MACROPHAGE STIMULATING PROTEIN [MSP] MATURATION | SOUTHERN RESEARCH INSTITUTE (US) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015184222-A1 | INHIBITORS OF HEPATOCYTE GROWTH FACTOR [HGF] AND MACROPHAGE STIMULATING PROTEIN [MSP] MATURATION | SOUTHERN RESEARCH INSTITUTE (US) | 2015-12-03 | — | — | WO | disclosed |