Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 12/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655137 | 0.80 | RAB9A (0.43) | EPHX2ALDH1A1MAPTTSHR | |
| SCHEMBL3658726 | 0.76 | CYP1A2 (0.44) | ALDH1A1MAPT | |
| SCHEMBL3654285 | 0.75 | MAPT (0.38) | MAPT | |
| SCHEMBL3648133 | 0.74 | LMNA (0.41) | ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL3655804 | 0.73 | CYP1A2 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL3651075 | 0.73 | CYP1A2 (0.40) | ALDH1A1HTTMAPT | |
| SCHEMBL3656686 | 0.72 | EPHX2 (0.38) | EPHX2MAPT | |
| SCHEMBL2472659 | 0.71 | — | — | |
| SCHEMBL3657543 | 0.71 | NPC1 (0.40) | ALDH1A1HTTMAPT | |
| SCHEMBL3703939 | 0.71 | RAB9A (0.42) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215058-B1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE UREAS AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2011-11-23 | — | — | EP | claimed |