Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 9/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420503 | 0.83 | CNR2 (0.55) | CNR2MEN1KMT2AMMP2MMP1 | |
| SCHEMBL10607094 | 0.81 | CNR2 (0.52) | CNR2MEN1KMT2AMMP2MMP1 | |
| SCHEMBL8665977 | 0.81 | CNR2 (0.52) | CNR2MEN1KMT2AMMP2MMP1 | |
| Benzylamine SCHEMBL9879869 | 0.81 | CSNK1E (0.42) | CNR2HDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL10605377 | 0.81 | HDAC8 (0.49) | MEN1KMT2AHDAC8HDAC3HDAC6 | |
| SCHEMBL23728326 | 0.80 | FAAH (0.55) | CNR2MEN1KMT2AHDAC8HDAC3 | |
| SCHEMBL23728411 | 0.80 | FAAH (0.55) | CNR2MEN1KMT2AHDAC8HDAC3 | |
| SCHEMBL10604618 | 0.78 | CA2 (0.46) | — | |
| SCHEMBL5599307 | 0.77 | MMP2 (0.59) | MEN1KMT2AHDAC8HDAC3HDAC6 | |
| SCHEMBL5599303 | 0.77 | MMP2 (0.59) | MEN1KMT2AHDAC8HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-B1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS CO LTD (JP) | 2011-11-30 | — | — | EP | claimed |
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |
| EP-1468994-B1 | Process for preparing cyclic amine substituted phenyl-alkyl-ketones | BASF SE (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-0805152-B1 | Cyclic amine substituted phenyl-alkyl-ketone and process for its preparation | CIBA SC HOLDING AG (CH) | 2005-06-08 | — | — | EP | disclosed |
| EP-1468994-A1 | Process for preparing cyclic amine substituted phenyl-alkyl-ketones | Ciba SC Holding AG (CH) | 2004-10-20 | — | — | EP | disclosed |
| EP-0805152-A3 | Cyclic amine substituted phenyl-alkyl-ketone and process for its preparation | Ciba SC Holding AG (CH) | 1998-01-28 | — | — | EP | disclosed |
| EP-0805152-A2 | Cyclic amine substituted phenyl-alkyl-ketone and process for its preparation | Ciba SC Holding AG (CH) | 1997-11-05 | — | — | EP | disclosed |