Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727775 | 0.93 | HRH3 (0.46) | HRH3ACACBMCHR1MAPTTP53 | |
| SCHEMBL1728927 | 0.90 | HRH3 (0.47) | HRH3ACACBMCHR1MAPTTP53 | |
| SCHEMBL1729221 | 0.85 | HRH3 (0.48) | HRH3ACACBMCHR1MAPTTP53 | |
| SCHEMBL1729308 | 0.78 | HRH3 (0.44) | HRH3ACACBMCHR1KCNH2 | |
| SCHEMBL1730142 | 0.78 | ABL1 (0.37) | HRH3MCHR1MAPTTP53ALDH1A1 | |
| SCHEMBL1728165 | 0.76 | KDM4E (0.45) | HRH3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1729776 | 0.76 | HRH3 (0.47) | HRH3ACACBMAPTNAPEPLDALDH1A1 | |
| SCHEMBL1729370 | 0.75 | HRH3 (0.43) | HRH3ACACBALDH1A1KDM4EKCNH2 | |
| SCHEMBL1727901 | 0.74 | SETDB1 (0.38) | HRH3MAPTTP53ALDH1A1KMT2A | |
| SCHEMBL1727774 | 0.73 | HRH3 (0.48) | HRH3ACACBMCHR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |