Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729370 | 0.89 | HRH3 (0.43) | KDM4EALDH1A1HRH3PDE10AHTR3E | |
| SCHEMBL1730195 | 0.89 | HCAR2 (0.46) | ALDH1A1HTR3AHRH4HCAR2SMN1; SMN2 | |
| SCHEMBL1728881 | 0.88 | HCAR2 (0.36) | KDM4EALDH1A1PDE10AHCAR2 | |
| SCHEMBL1727892 | 0.87 | HTR1A (0.39) | KDM4EALDH1A1HRH3HTR3AHCAR2 | |
| SCHEMBL1727648 | 0.87 | MAPT (0.34) | KDM4EALDH1A1PDE10AHTR3AHPGD | |
| SCHEMBL1729308 | 0.87 | HRH3 (0.44) | HRH3PDE10AHTR3EHTR3BHTR3A | |
| SCHEMBL1727901 | 0.86 | SETDB1 (0.38) | KDM4EALDH1A1HSD17B10HRH3HCAR2 | |
| SCHEMBL1728927 | 0.86 | HRH3 (0.47) | KDM4EALDH1A1HSD17B10HRH3HPGD | |
| SCHEMBL1729592 | 0.85 | PTGES (0.42) | PDE10APDE2A | |
| SCHEMBL1727957 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1CYP3A4HSD17B10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |