Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729370 | 0.95 | HRH3 (0.43) | HRH3HTR3AHRH4ACACBPDE10A | |
| SCHEMBL1728927 | 0.88 | HRH3 (0.47) | HRH3ACACBMCHR1KCNH2 | |
| SCHEMBL1728165 | 0.87 | KDM4E (0.45) | HRH3HTR3AHRH4PDE10APDE2A | |
| SCHEMBL1729779 | 0.87 | SMO (0.34) | PDE10APDE2AF10DGAT1KCNH2 | |
| SCHEMBL1727926 | 0.86 | HRH3 (0.46) | HRH3HTR3AHRH4ACACBPDE10A | |
| SCHEMBL1727892 | 0.84 | HTR1A (0.39) | HRH3HTR3AHTR1A | |
| SCHEMBL1728881 | 0.83 | HCAR2 (0.36) | PDE10A | |
| SCHEMBL1729592 | 0.82 | PTGES (0.42) | PDE10APDE2AFAAH | |
| SCHEMBL1730418 | 0.82 | HRH3 (0.45) | HRH3HTR3AHRH4ACACBPDE10A | |
| SCHEMBL1727558 | 0.81 | KCNH2 (0.40) | MCHR1DGAT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |