SCHEMBL17299577

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21703737	0.85	KIF11 (0.44)	KIF11TNKSTNKS2MAPTAPEX1
	SCHEMBL15893371	0.84	TNKS (0.39)	KIF11TNKSTNKS2APEX1TNF
	SCHEMBL17299516	0.83	KIF11 (0.55)	KIF11TNKSTNKS2MAPTRAB9A
	SCHEMBL12060917	0.83	GPR3 (0.54)	KIF11TNKSTNKS2MAPTAPEX1
	SCHEMBL17299458	0.81	GPR3 (0.54)	TNKSTNKS2MAPTGPR3ALDH1A1
	SCHEMBL24245795	0.81	ALDH1A1 (0.37)	KIF11TNKSTNKS2ALDH1A1L3MBTL1
	SCHEMBL25817286	0.79	KIF11 (0.42)	KIF11TNKSTNKS2MAPTAPEX1
	SCHEMBL25682452	0.79	KIF11 (0.40)	KIF11TNKSTNKS2MAPTAPEX1
	SCHEMBL23917959	0.78	KIF11 (0.41)	KIF11TNKSTNKS2MAPTAPEX1
	SCHEMBL25682428	0.78	KIF11 (0.42)	KIF11TNKSTNKS2MAPTGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.