Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061111 | 0.88 | CALM1 (0.44) | CALM1CAMKK2TAAR1HTTRIPK1 | |
| SCHEMBL13005575 | 0.85 | CALM1 (0.41) | CALM1CAMKK2TAAR1HTTRIPK1 | |
| SCHEMBL24899621 | 0.76 | CALM1 (0.46) | CALM1CAMKK2TAAR1HTTALDH1A1 | |
| SCHEMBL13005676 | 0.76 | CALM1 (0.45) | CALM1CAMKK2TAAR1HTTKDM4E | |
| SCHEMBL13061135 | 0.72 | CALM1 (0.44) | CALM1CAMKK2TAAR1HTTKDM4E | |
| SCHEMBL13005634 | 0.72 | CALM1 (0.42) | CALM1CAMKK2TAAR1HTTKDM4E | |
| SCHEMBL171456 | 0.72 | CALM1 (0.46) | CALM1CAMKK2BCHE | |
| SCHEMBL2464280 | 0.70 | ALDH1A1 (0.54) | TAAR1ALDH1A1TSHRNOS3NOS1 | |
| SCHEMBL13060692 | 0.70 | TAAR1 (0.57) | CALM1CAMKK2TAAR1HTTRIPK1 | |
| SCHEMBL13060704 | 0.69 | CALM1 (0.49) | CALM1CAMKK2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768966-B1 | COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY INC (US) | 2012-03-07 | — | — | EP | disclosed |