Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 5/20 | 0.53 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.48 |
| ▸ | NOS2 | P35228 | 4/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989636 | 0.89 | ALDH1A1 (0.67) | ALDH1A1TSHRNOS1HTR7CHRNB2 | |
| SCHEMBL4449176 | 0.83 | TAAR1 (0.57) | ALDH1A1TSHRNOS1LOXL2SMN1; SMN2 | |
| Benzylamine SCHEMBL28220473 | 0.83 | ALDH1A1 (0.74) | ALDH1A1TSHRNOS1LOXL2SMN1; SMN2 | |
| Benzylamine SCHEMBL28220474 | 0.83 | ALDH1A1 (0.74) | ALDH1A1TSHRNOS1LOXL2SMN1; SMN2 | |
| SCHEMBL4917916 | 0.82 | CHRNB2 (0.50) | ALDH1A1NOS1PNMTENPP2LOXL2 | |
| SCHEMBL3972958 | 0.81 | HRH3 (0.64) | ALDH1A1TSHRNOS1LOXL2NOS2 | |
| SCHEMBL1873058 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRNOS1NOS2NOS3 | |
| SCHEMBL10422276 | 0.81 | LOXL2 (0.71) | ALDH1A1NOS1PNMTENPP2LOXL2 | |
| SCHEMBL36008 | 0.81 | LOXL2 (0.71) | ALDH1A1NOS1PNMTENPP2LOXL2 | |
| SCHEMBL13462516 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRNOS1HTR7CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534474-B2 | Dihydrofuropyridine derivatives as rho-kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2026-01-27 | — | — | US | disclosed |
| EP-4263547-B1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2025-07-02 | — | — | EP | disclosed |
| EP-4263546-B1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2025-07-02 | — | — | EP | disclosed |
| CN-117924694-A | Preparation method of MXD6 | 万华化学集团股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-02 | — | — | US | disclosed |
| US-20240092792-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-21 | — | — | US | disclosed |
| US-20240082223-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-14 | — | — | US | disclosed |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | THE SCRIPPS RESEARCH INSTITUTE | 2022-06-30 | — | — | US | disclosed |
| CN-114127050-A | Benzopyran and imidazole derivatives useful for stabilizing amyloidogenic immunoglobulin light chains | 斯克利普斯研究所 | 2022-03-01 | — | — | CN | disclosed |
| EP-3946604-A1 | BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | The Scripps Research Institute (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-0566536-A1 | Electrically conducting polymer compositions and their use | Japat Ltd (CH) | 1993-10-20 | — | — | EP | disclosed |
| EP-0560721-A2 | Sheet-like heating elements and preparation thereof | Japat Ltd (CH) | 1993-09-15 | — | — | EP | disclosed |
| US-5206297-A | ELECTRICALLY CONDUCTIVE MOULDING COMPOSITIONS AND FILLERS FROM POLYHETEROAROMATIC COMPOUNDS AND POLYMERIC SULFATES | CIBA-GEIBY CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |
| US-5200113-A | Molding materials, sheets, filaments, composites | CIBA-GEIGY CORPORATION (US) | 1993-04-06 | — | — | US | disclosed |
| US-5077156-A | ANTISTATIC AND ELECTRICALLY CONDUCTIVE RELIEF IMAGES, PROCESSES FOR THE PRODUCTION THEREOF, COATING AGENTS AND RADIATION-SENSITIVE POLYMERS | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| US-5061401-A | Thermoplastic processing; tensile and flexural strength; films; electrodes, filalments; electromagnetic screening | CIBA-GEIGY CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| EP-0446172-A2 | Electrical conductive press masses and polyheteroaromates and polymere sulfate fillers | CIBA-GEIGY AG (CH) | 1991-09-11 | — | — | EP | disclosed |
| EP-0362143-A2 | Antistatic and electrically conductive relief images, process for manufacturing the same, coating material and radiation-sensitive polymers | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | disclosed |
| EP-0362142-A2 | Antistatic and electrically conductive composition | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | disclosed |
| EP-0358188-A2 | Electrically conductive composition with polyheteroaromates and polymer sulfates | Japat Ltd (CH) | 1990-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092792-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS | ROCK1, ROCK2, RHOA | ALDH1A1 1029/4885TSHR 4675/4885NOS1 63/4885 |
| US-12534474-B2 | Dihydrofuropyridine derivatives as rho-kinase inhibitors | ROCK1, RHOC, ROCK2 | ALDH1A1 1959/4885TSHR 3258/4885NOS1 324/4885 |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | TTR, MAP1LC3B, SAAL1 | ALDH1A1 2072/4885TSHR 3610/4885NOS1 4098/4885 |
| US-20240082223-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS | ROCK1, ROCK2, RHOA | ALDH1A1 1029/4885TSHR 4675/4885NOS1 63/4885 |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | TTR, MAP1LC3B, SAAL1 | ALDH1A1 2072/4885TSHR 3610/4885NOS1 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.