Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.52 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.52 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 1/20 | 0.52 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301080 | 0.87 | THRA (0.50) | THRATHRB | |
| SCHEMBL7616848 | 0.83 | S1PR1 (0.47) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL7620688 | 0.83 | S1PR1 (0.47) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL7623202 | 0.83 | S1PR1 (0.47) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL8529514 | 0.81 | S1PR1 (0.48) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL8498503 | 0.81 | S1PR1 (0.48) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL4917300 | 0.81 | S1PR1 (0.48) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL8498832 | 0.81 | S1PR1 (0.48) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL17301077 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SLC6A3LMNAPTGS2 | |
| SCHEMBL7618064 | 0.80 | TNNC1 (0.44) | S1PR1TNNC1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732030-B2 | Process for the preparation of fingolimod and its salts | SHILPA MEDICARE LIMITED (IN) | 2017-08-15 | — | — | US | disclosed |
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | S1PR4, S1PR1, S1PR5 | S1PR1 2/4885TNNC1 4581/4885S1PR4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.