Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.50 |
| ▸ | THRB | P10828 | 9/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.49 |
| ▸ | STS | P08842 | 4/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301079 | 0.87 | S1PR1 (0.52) | THRATHRB | |
| SCHEMBL7623199 | 0.85 | THRA (0.46) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL7622013 | 0.85 | THRA (0.46) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL7622400 | 0.85 | THRA (0.46) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL15894876 | 0.84 | THRA (0.46) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL8520804 | 0.83 | THRA (0.45) | THRATHRBHSD17B3STS | |
| SCHEMBL7613374 | 0.82 | THRA (0.45) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL7714029 | 0.82 | THRA (0.45) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL8501592 | 0.82 | THRA (0.57) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL4293988 | 0.82 | THRA (0.57) | THRATHRBHSD17B3STSHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732030-B2 | Process for the preparation of fingolimod and its salts | SHILPA MEDICARE LIMITED (IN) | 2017-08-15 | — | — | US | disclosed |
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | S1PR4, S1PR1, S1PR5 | THRA 2574/4885THRB 1347/4885HSD17B3 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.