Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729061 | 0.92 | DGAT1 (0.46) | DEGS1DGAT1KCNH2KDM4ELMNA | |
| SCHEMBL1728906 | 0.89 | DEGS1 (0.48) | DEGS1PDE10ADGAT1KCNH2KDM4E | |
| SCHEMBL1730190 | 0.87 | CHRM4 (0.44) | DEGS1PDE10ADGAT1KDM4ELMNA | |
| SCHEMBL1729688 | 0.85 | LMNA (0.59) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL1727978 | 0.85 | KDM1A (0.43) | DGAT1KDM4ELMNAABL1MAPT | |
| SCHEMBL1727605 | 0.84 | DGAT1 (0.44) | DGAT1KCNH2KDM4ELMNAABL1 | |
| SCHEMBL1730416 | 0.84 | HRH3 (0.47) | PDE10ADGAT1KCNH2AOC3 | |
| SCHEMBL1727924 | 0.84 | HRH3 (0.48) | PDE10ADGAT1KCNH2PPARGPPARD | |
| SCHEMBL1727916 | 0.83 | ENPP2 (0.45) | DGAT1KDM4ELMNAABL1GPR119 | |
| SCHEMBL1727588 | 0.82 | AOC3 (0.48) | DGAT1KCNH2GPR119KDM1AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |