Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730164 | 0.89 | DEGS1 (0.47) | DEGS1PDE10ADGAT1KCNH2GPR119 | |
| SCHEMBL1727687 | 0.87 | PDE10A (0.43) | DEGS1PDE10ADGAT1LMNAKDM1A | |
| SCHEMBL1730318 | 0.87 | HRH3 (0.43) | PDE10ADGAT1GPR119LMNADRD2 | |
| SCHEMBL1729359 | 0.85 | KDM1A (0.45) | LMNAKDM1ATNFSTAT3SMN1; SMN2 | |
| SCHEMBL1729795 | 0.84 | LMNA (0.60) | LMNASMN1; SMN2KDM4EMAPTABL1 | |
| SCHEMBL1729679 | 0.84 | CHRM4 (0.48) | KCNH2GPR119 | |
| SCHEMBL1727662 | 0.83 | HTR1A (0.43) | DGAT1KCNH2LMNAKDM1AKDM4E | |
| SCHEMBL1728863 | 0.82 | HRH3 (0.49) | PDE10ADGAT1KCNH2ADORA2AHTR1A | |
| SCHEMBL1729061 | 0.81 | DGAT1 (0.46) | DEGS1DGAT1KCNH2LMNACNR2 | |
| SCHEMBL1729166 | 0.80 | LMNA (0.39) | LMNAKDM1ASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |