Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727885 | 0.92 | KDM4E (0.41) | FFAR4P2RX7HTR1ADRD2HTR7 | |
| SCHEMBL1728840 | 0.91 | HTR1A (0.39) | FFAR4P2RX7HTR1ADRD2HTR7 | |
| SCHEMBL1730021 | 0.84 | HTR1A (0.41) | FFAR4P2RX7HTR1ADRD2HTR7 | |
| SCHEMBL1729231 | 0.82 | KDM4E (0.40) | FFAR4P2RX7HTR1ADRD2HTR7 | |
| SCHEMBL1727856 | 0.82 | KMT2A (0.40) | HTR1AKDM4ERECQLRBP4TTR | |
| SCHEMBL1728987 | 0.81 | KDM4E (0.61) | DRD2KDM4ERECQLMAPT | |
| SCHEMBL1727662 | 0.79 | HTR1A (0.43) | HTR1AKDM4ECKS1BSKP1SKP2 | |
| SCHEMBL1727778 | 0.78 | P2RX7 (0.53) | FFAR4P2RX7HTR1ADRD2HTR7 | |
| SCHEMBL1729255 | 0.78 | HTR1A (0.43) | FFAR4HTR1ADRD2HTR7CYP3A4 | |
| SCHEMBL1728967 | 0.76 | NSD2 (0.47) | P2RX7HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |