Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729231 | 0.92 | KDM4E (0.40) | HTR1ADRD2HTR7HTR6FFAR4 | |
| SCHEMBL1730244 | 0.91 | FFAR4 (0.40) | HTR1ADRD2HTR7HTR6FFAR4 | |
| SCHEMBL1730021 | 0.83 | HTR1A (0.41) | HTR1ADRD2HTR7HTR6FFAR4 | |
| SCHEMBL1727905 | 0.82 | KMT2A (0.39) | RBP4TTRKDM4ERECQLKMT2A | |
| SCHEMBL1727885 | 0.82 | KDM4E (0.41) | HTR1ADRD2HTR7HTR6FFAR4 | |
| SCHEMBL1728989 | 0.80 | SIRT2 (0.40) | RBP4TTRACHE | |
| SCHEMBL1727605 | 0.80 | DGAT1 (0.44) | HTR1AKDM4ECKS1BSKP1SKP2 | |
| SCHEMBL1728967 | 0.79 | NSD2 (0.47) | HTR1ADRD2HTR7HTR6RBP4 | |
| SCHEMBL1728786 | 0.79 | HTR1A (0.42) | HTR1ADRD2HTR7FFAR4CKS1B | |
| SCHEMBL1729384 | 0.78 | DPP4 (0.44) | DRD2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |