Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 4/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730153 | 0.91 | CHRM4 (0.52) | NSD2CHRM4HTR1ADRD2HTR7 | |
| SCHEMBL1727778 | 0.89 | P2RX7 (0.53) | HTR1ADRD2HTR7HTR6P2RX7 | |
| SCHEMBL3269154 | 0.85 | HTR1A (0.43) | NSD2CHRM4HTR1ADRD2HTR7 | |
| SCHEMBL1729840 | 0.81 | KMT2A (0.45) | HTR1ADRD2HTR7HTR6P2RX7 | |
| SCHEMBL1727773 | 0.80 | P2RX7 (0.54) | HTR1ADRD2HTR7HTR6P2RX7 | |
| SCHEMBL1730203 | 0.80 | CHRM4 (0.51) | NSD2CHRM4 | |
| SCHEMBL1727887 | 0.80 | KDM4E (0.60) | CHRM4DRD2 | |
| SCHEMBL344551 | 0.79 | CHRM4 (0.60) | CHRM4DRD2CHRM2 | |
| SCHEMBL1728840 | 0.79 | HTR1A (0.39) | HTR1ADRD2HTR7HTR6P2RX7 | |
| SCHEMBL2323704 | 0.78 | CHRM4 (0.50) | CHRM4CHRM2CHRM1CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |