Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | RBP4 | P02753 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | LCAT | P04180 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730046 | 0.82 | DKK1 (0.49) | KDM4E | |
| SCHEMBL346096 | 0.78 | CHRM4 (0.43) | CHRM4RBP4ADRB1PKMSLC6A7 | |
| SCHEMBL2834267 | 0.77 | ADRB1 (0.61) | CHRM4RBP4ADRB1PKMSLC6A7 | |
| SCHEMBL1729795 | 0.76 | LMNA (0.60) | CHRM4PKMCHRM2KMT2AKDM4E | |
| SCHEMBL346219 | 0.76 | CHRM4 (0.45) | CHRM4RBP4ADRB1PKMSLC6A7 | |
| SCHEMBL1728756 | 0.76 | CHRM4 (0.59) | CHRM4RBP4ADRB1PKMSLC6A7 | |
| SCHEMBL2330983 | 0.76 | ADRB1 (0.53) | CHRM4RBP4ADRB1PKMSLC6A7 | |
| SCHEMBL2330479 | 0.75 | ADRB1 (0.53) | CHRM4RBP4ADRB1PKMSLC6A7 | |
| SCHEMBL2324834 | 0.75 | CHRM4 (0.68) | CHRM4RBP4ADRB1PKMSLC6A7 | |
| SCHEMBL895533 | 0.75 | KDM4E (0.60) | CHRM4RBP4ADRB1PKMSLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |