SCHEMBL2643485

SCHEMBL2643485

C1=CC2=Cc3ccccc3NC2C=C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5904469 0.78 TNKS2 (0.36) GAA
SCHEMBL5531635 0.77 TNKS2 (0.36) MAPT
SCHEMBL20067379 0.73 PBRM1 (0.31) GAA
SCHEMBL20067380 0.73 BRD4 (0.31)
SCHEMBL16772246 0.72 GAA (0.31) GAAMAPT
SCHEMBL12143219 0.72 GAA (0.39) GAAMAPT
SCHEMBL460544 0.71 GAA (0.36) GAAMAPT
SCHEMBL11458282 0.71 PARP1 (0.36)
SCHEMBL869745 0.70
SCHEMBL12096478 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472230-B1 ANSAMYCINS HAVING IMPROVED PHARMACOLOGICAL AND BIOLOGICAL PROPERTIES CONFORMA THERAPEUTICS CORP (US) 2009-06-17 EP claimed
US-20250268015-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2025-08-21 US disclosed
CN-109988144-B Aromatic vinyl or aromatic ethyl derivative, preparation method, intermediate, pharmaceutical composition and application thereof 广州再极医药科技有限公司 2024-07-05 CN disclosed
EP-4265624-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-10-25 EP disclosed
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND LG CHEM, LTD. (KR) 2023-10-05 US disclosed
EP-4194460-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND Lg Chem, Ltd. (KR) 2023-06-14 EP disclosed
CN-115989725-A Compound and organic light emitting device including the same 株式会社LG化学 2023-04-18 CN disclosed
CN-115968592-A Organic light emitting device comprising organic compound 株式会社LG化学 2023-04-14 CN disclosed
WO-2022139525-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND 주식회사 엘지화학 2022-06-30 WO disclosed
WO-2022139513-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-06-30 WO disclosed
US-20180105534-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE NANJING TOPTO MATERIALS CO.,LTD. (CN) 2018-04-19 US disclosed
US-20180105534-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE NANJING TOPTO MATERIALS CO.,LTD. (CN) 2018-04-19 US disclosed
WO-2009004146-A2 NOVEL HERBIMYCIN A ANALOGUE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF SANOFI-AVENTIS (FR) 2009-01-08 WO disclosed
EP-1406620-B1 VINYL PHENYL DERIVATIVES AS GLK ACTIVATORS ASTRAZENECA AB (SE) 2006-11-02 EP disclosed
WO-1999051223-A1 BENZOQUINOID ANSAMYCINS FOR THE TREATMENT OF CARDIAC ARREST AND STROKE UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1999-10-14 WO disclosed
US-3886165-A Indolylimidoylheterocyclics MEAD JOHNSON & CO 1975-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180105534-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE PNMT, H1-0, H1-10 GAA 2709/4885MAPT 3451/4885
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND CYP1A1, AOX1, CYP1B1 GAA 2399/4885MAPT 1319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.