Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307272 | 0.78 | SMN1; SMN2 (0.36) | MAPK1 | |
| SCHEMBL23308913 | 0.77 | TP53 (0.62) | TP53KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL12311850 | 0.75 | ALDH1A1 (0.46) | TP53KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL21419466 | 0.74 | MAPT (0.44) | TP53KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL29375776 | 0.72 | LMNA (0.39) | TP53KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL200412 | 0.72 | GABRA1 (0.43) | TP53ALDH1A1LMNACYP3A4HPGD | |
| SCHEMBL12311819 | 0.72 | CA2 (0.48) | TP53KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL23308949 | 0.72 | TP53 (0.42) | TP53KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL12311889 | 0.71 | MAPT (0.44) | TP53KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL5962399 | 0.70 | CA1 (0.50) | TP53MAPTALDH1A1MAPK1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351761-B1 | NOVEL METAL COMPLEX, AND METHOD FOR PRODUCING -OLEFIN POLYMER AND METHOD FOR PRODUCING -OLEFIN/(METH)ACRYLATE COPOLYMER EACH USING THE METAL COMPLEX | JAPAN POLYPROPYLENE CORP (JP) | 2015-12-02 | — | — | EP | disclosed |