Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.37 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.37 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.37 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.37 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809094 | 0.82 | ALDH1A1 (0.59) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL2095064 | 0.82 | ALDH1A1 (0.69) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL21263 | 0.82 | ALDH1A1 (0.69) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL811578 | 0.82 | ALDH1A1 (0.59) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL28298270 | 0.79 | ALDH1A1 (0.65) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL1816933 | 0.79 | ALDH1A1 (0.65) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL12231 | 0.73 | ALDH1A1 (0.48) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL7590401 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CYP1A1CYP1B1CYP3A4CYP1A2 | |
| SCHEMBL2091396 | 0.73 | — | — | |
| SCHEMBL291988 | 0.71 | CYP3A4 (0.55) | ALDH1A1AHRKDM1ACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150353559-A1 | NEW BICYCLIC DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353559-A1 | NEW BICYCLIC DERIVATIVES | BICRA, CCNY, UQCRB | ALDH1A1 725/4885AHR 301/4885KDM1A 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.