Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.48 |
| ▸ | AHR | P35869 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.42 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.42 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.42 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.42 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21263 | 0.97 | ALDH1A1 (0.69) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| SCHEMBL28298270 | 0.94 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| SCHEMBL811578 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| SCHEMBL15521815 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| SCHEMBL12231 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| SCHEMBL19088278 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| 1,3,5-Trimethoxybenzene SCHEMBL28493 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| SCHEMBL15936165 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| SCHEMBL17310933 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP1A1CYP1B1AHRCYP3A4 | |
| SCHEMBL1477524 | 0.79 | ALDH1A1 (0.46) | ALDH1A1AHRNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266532-B2 | Tricyclic modulators of TNF signaling | ABBVIE INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20180179198-A1 | TRICYCLIC MODULATORS OF TNF SIGNALING | ABBVIE INC. | 2018-06-28 | — | — | US | disclosed |
| US-9856253-B2 | Tricyclic modulators of TNF signaling | ABBVIE, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160304517-A1 | TRICYCLIC MODULATORS OF TNF SIGNALING | ABBVIE INC. | 2016-10-20 | — | — | US | disclosed |
| CN-102781583-B | Metathesis catalyst and process for use thereof | EXXONMOBIL CHEM PATENTS INC | 2015-07-22 | — | — | CN | disclosed |
| EP-2866936-A1 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2015-05-06 | — | — | EP | disclosed |
| CN-104394987-A | Metathesis catalyst and process for use thereof | EXXONMOBIL CHEM PATENTS INC | 2015-03-04 | — | — | CN | disclosed |
| US-8809563-B2 | Metathesis catalyst and process for use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-08-19 | — | — | US | disclosed |
| CN-102186834-B | New herbicides | SYNGENTA LTD | 2014-08-13 | — | — | CN | disclosed |
| CN-103781752-A | Method for producing alpha-hydroxy ketone compound | SUMITOMO CHEMICAL CO | 2014-05-07 | — | — | CN | disclosed |
| WO-2014004089-A1 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-01-03 | — | — | WO | disclosed |
| EP-2533899-A2 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20120289729-A1 | Metathesis Catalyst and Process for Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-11-15 | — | — | US | disclosed |
| US-8237003-B2 | Metathesis catalyst and process for use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-08-07 | — | — | US | disclosed |
| CN-102186834-A | New herbicides | SYNGENTA LTD | 2011-09-14 | — | — | CN | disclosed |
| WO-2011100022-A2 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-08-18 | — | — | WO | disclosed |
| US-20110112349-A1 | Metathesis Catalyst and Process for Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289729-A1 | Metathesis Catalyst and Process for Use Thereof | MGLL, FASN, FDFT1 | ALDH1A1 2327/4885CYP1A1 556/4885CYP1B1 569/4885 |
| US-20160304517-A1 | TRICYCLIC MODULATORS OF TNF SIGNALING | TNF, TNFRSF1A, CD40 | ALDH1A1 1896/4885CYP1A1 759/4885CYP1B1 822/4885 |
| US-10266532-B2 | Tricyclic modulators of TNF signaling | TNF, TNFRSF1A, CD40 | ALDH1A1 1896/4885CYP1A1 759/4885CYP1B1 822/4885 |
| US-20110112349-A1 | Metathesis Catalyst and Process for Use Thereof | MGLL, FASN, MSMO1 | ALDH1A1 1338/4885CYP1A1 85/4885CYP1B1 333/4885 |
| US-20180179198-A1 | TRICYCLIC MODULATORS OF TNF SIGNALING | TNF, TNFRSF1A, CD40 | ALDH1A1 1896/4885CYP1A1 759/4885CYP1B1 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.