SCHEMBL17311166

SCHEMBL17311166

Fc1ccc(-c2cccc(-c3ccccn3)c2)c(F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 3/20 0.48
PTGER1 P34995 1/20 0.44
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
PDK2 Q15119 1/20 0.43
ALOX5AP P20292 3/20 0.42
FEN1 P39748 3/20 0.42
TGFBR1 P36897 2/20 0.42
KAT6A Q92794 1/20 0.41
MAPK14 Q16539 1/20 0.41
METAP2 P50579 1/20 0.41
METAP1 P53582 1/20 0.41
CBFB Q13951 1/20 0.41
CDC7 O00311 1/20 0.41
ROCK2 O75116 1/20 0.41
MAP4K4 O95819 1/20 0.41
PIM1 P11309 1/20 0.41
PRKACA P17612 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397311 1.00 GRM5 (0.48) GRM5PTGER1MEN1NPC1RAB9A
SCHEMBL3773686 0.98 GRM5 (0.47) GRM5PTGER1MEN1NPC1RAB9A
SCHEMBL28406712 0.87 TGFBR1 (0.50) GRM5MEN1NPC1RAB9AKMT2A
SCHEMBL3779014 0.86 GRM5 (0.59) GRM5PTGER1RAB9APDK2TGFBR1
SCHEMBL2483821 0.85 TGFBR1 (0.51) GRM5NPC1RAB9APDK2ALOX5AP
SCHEMBL3773646 0.84 TGFBR1 (0.50) GRM5NPC1RAB9APDK2ALOX5AP
SCHEMBL29353368 0.83 MEN1 (0.52) GRM5MEN1NPC1RAB9AKMT2A
SCHEMBL29352118 0.83 MEN1 (0.52) GRM5MEN1NPC1RAB9AKMT2A
SCHEMBL514547 0.83 MEN1 (0.52) GRM5MEN1NPC1RAB9AKMT2A
SCHEMBL16139767 0.82 KMO (0.47) PTGER1MEN1RAB9AKMT2AFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106058-A Preparation method and application of aggregation-induced emission platinum complex 大连理工大学 2022-03-01 CN claimed
US-9312503-B2 Green light iridium (III) complex and a method of preparing the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-04-12 US claimed
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-12-10 US claimed
CN-114106058-B Preparation method and application of aggregation-induced emission platinum complex 大连理工大学 2023-09-12 CN disclosed
CN-114106058-A Preparation method and application of aggregation-induced emission platinum complex 大连理工大学 2022-03-01 CN disclosed
US-9312503-B2 Green light iridium (III) complex and a method of preparing the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-04-12 US disclosed
US-9312503-B2 Green light iridium (III) complex and a method of preparing the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-04-12 US disclosed
US-9312503-B2 Green light iridium (III) complex and a method of preparing the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-04-12 US disclosed
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-12-10 US disclosed
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-12-10 US disclosed
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME ALG3, RTN3, GPR3 GRM5 305/4885PTGER1 721/4885MEN1 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.