SCHEMBL3773646

SCHEMBL3773646

Fc1ccccc1-c1cccc(-c2ccccn2)c1.Fc1ccccc1-c1cccc(-c2ccccn2)c1.Fc1ccccc1-c1cccc(-c2ccccn2)c1.[Ir]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.50
GRM5 P41594 4/20 0.46
KAT6A Q92794 1/20 0.46
DRD2 P14416 1/20 0.45
DRD4 P21917 1/20 0.45
DRD3 P35462 1/20 0.45
PDK2 Q15119 1/20 0.44
CYP2A6 P11509 1/20 0.43
HTR1A P08908 1/20 0.42
HTR7 P34969 1/20 0.42
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
KDM4E B2RXH2 3/20 0.42
LMNA P02545 2/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2483821 0.98 TGFBR1 (0.51) TGFBR1GRM5KAT6ADRD2DRD4
SCHEMBL3774471 0.90 TGFBR1 (0.45) TGFBR1GRM5KAT6APDK2CYP2A6
SCHEMBL3773686 0.86 GRM5 (0.47) TGFBR1GRM5KAT6APDK2CYP2A6
SCHEMBL3779014 0.86 GRM5 (0.59) TGFBR1GRM5KAT6APDK2CYP2A6
SCHEMBL17426491 0.86 KDM4E (0.52) TGFBR1GRM5PDK2CYP2A6HTR1A
SCHEMBL17311166 0.84 GRM5 (0.48) TGFBR1GRM5KAT6APDK2CYP2A6
SCHEMBL29397311 0.84 GRM5 (0.48) TGFBR1GRM5KAT6APDK2CYP2A6
SCHEMBL28714019 0.82 KDM4E (0.48) TGFBR1GRM5PDK2CYP2A6ALOX5AP
SCHEMBL502867 0.82 KDM4E (0.62) GRM5KAT6ACYP2A6HTR1AHTR7
SCHEMBL29679578 0.82 KDM4E (0.62) GRM5KAT6ACYP2A6HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3855519-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2021-07-28 EP disclosed
EP-3428986-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2021-01-20 EP disclosed
US-8603645-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2013-12-10 US disclosed
US-8449990-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2013-05-28 US disclosed
US-20110060143-A1 Stable and Efficient Electroluminescent Materials KWONG RAYMOND 2011-03-10 US disclosed
US-7851072-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2010-12-14 US disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110060143-A1 Stable and Efficient Electroluminescent Materials EML4, ITGA5, CHRM5 TGFBR1 2435/4885GRM5 38/4885KAT6A 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.