Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099774 | 0.72 | GRM6 (0.40) | KMT2AGRM6OPRK1LMNACYP2D6 | |
| SCHEMBL2841486 | 0.72 | CHRM2 (0.49) | KMT2AL3MBTL1OPRK1CHRM2CHRM4 | |
| SCHEMBL4477292 | 0.72 | CHRM2 (0.49) | KMT2AL3MBTL1OPRK1CHRM2CHRM4 | |
| SCHEMBL2841484 | 0.72 | CHRM2 (0.49) | KMT2AL3MBTL1OPRK1CHRM2CHRM4 | |
| SCHEMBL23229353 | 0.71 | CHRM2 (0.51) | KMT2AL3MBTL1OPRK1CHRM2CHRM4 | |
| SCHEMBL21631545 | 0.71 | OPRK1 (0.46) | NR1H2KMT2AL3MBTL1USP2OPRK1 | |
| SCHEMBL21631548 | 0.71 | OPRK1 (0.46) | NR1H2KMT2AL3MBTL1USP2OPRK1 | |
| SCHEMBL11545110 | 0.71 | CHRM2 (0.47) | KMT2AL3MBTL1OPRK1CHRM2CHRM4 | |
| SCHEMBL11545113 | 0.71 | CHRM2 (0.47) | KMT2AL3MBTL1OPRK1CHRM2CHRM4 | |
| SCHEMBL21653769 | 0.70 | KMT2A (0.46) | NR1H2KMT2AL3MBTL1USP2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344019-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2019-07-09 | — | — | US | disclosed |
| US-20150353529-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344019-B2 | Antiviral compounds | MAVS, EIF2AK2, ZC3HAV1 | NR1H2 2557/4885KMT2A 3803/4885L3MBTL1 2200/4885 |
| US-20150353529-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | NR1H2 2557/4885KMT2A 3803/4885L3MBTL1 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.