Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011496 | 0.79 | HSD11B1 (0.38) | CYP2D6S1PR1S1PR5HSD11B1MEN1 | |
| SCHEMBL17311985 | 0.72 | NR1H2 (0.40) | GRM6CYP2D6S1PR1S1PR5OPRM1 | |
| SCHEMBL1012463 | 0.72 | FKBP1A (0.45) | KMT2A | |
| SCHEMBL10202890 | 0.71 | ALDH1A1 (0.60) | CYP2D6S1PR1S1PR5OPRM1OPRK1 | |
| SCHEMBL11093783 | 0.69 | CCR2 (0.41) | CYP2D6OPRK1HSD11B1AMPD2GAA | |
| SCHEMBL22443390 | 0.68 | GRM6 (0.51) | GRM6CYP2D6S1PR1S1PR5OPRK1 | |
| SCHEMBL1203078 | 0.68 | DRD2 (0.41) | OPRK1HSD11B1MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9837514 | 0.68 | KMT2A (0.40) | CYP2D6OPRK1MEN1LMNAKMT2A | |
| SCHEMBL1012462 | 0.68 | HSD11B1 (0.40) | CYP2D6OPRM1HSD11B1MEN1KMT2A | |
| SCHEMBL3250253 | 0.67 | OPRK1 (0.51) | OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |