Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.72 |
| ▸ | CA12 | O43570 | 3/20 | 0.72 |
| ▸ | CA1 | P00915 | 3/20 | 0.72 |
| ▸ | CA9 | Q16790 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GHSR | Q92847 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17327797 | 0.86 | KMT2A (0.64) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL16942603 | 0.85 | CA2 (0.74) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL19707622 | 0.84 | RAB9A (0.76) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL672750 | 0.84 | CA2 (1.00) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL24810807 | 0.82 | ALDH1A1 (0.50) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL17316231 | 0.81 | CA2 (0.70) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL4118082 | 0.80 | RAB9A (0.65) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL22187367 | 0.79 | CA2 (0.72) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL22588926 | 0.78 | RAB9A (0.67) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL4117858 | 0.78 | RAB9A (0.67) | CA2CA12CA1CA9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015188060-A1 | FLUOROSULFONYL sEH INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-12-10 | — | — | WO | disclosed |
| WO-2015188060-A1 | FLUOROSULFONYL sEH INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-12-10 | — | — | WO | disclosed |