Sugi Predict

Sugi Predict / Compounds / SCHEMBL22187367

SCHEMBL22187367

SCHEMBL22187367

CC(C)c1ccc(S(=O)(=O)Oc2ccc(NC(=O)Nc3ccc(OS(=O)(=O)c4ccc(C(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 6/20 0.72
▸ CA12 O43570 5/20 0.72
▸ CA1 P00915 5/20 0.72
▸ CA9 Q16790 5/20 0.72
▸ MEN1 O00255 3/20 0.64
▸ KMT2A Q03164 3/20 0.64
▸ RAB9A P51151 1/20 0.64
▸ ALDH1A1 P00352 4/20 0.54
▸ MAPT P10636 1/20 0.54
▸ RECQL P46063 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ HSP90AA1 P07900 1/20 0.53
▸ ENPP1 P22413 5/20 0.53
▸ ENPP3 O14638 4/20 0.53
▸ ENPP2 Q13822 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29673662 0.90 CA2 (0.60) CA2CA12CA1CA9MEN1
SCHEMBL22187154 0.90 CA2 (0.60) CA2CA12CA1CA9MEN1
SCHEMBL22588959 0.89 CA2 (0.66) CA2CA12CA1CA9MEN1
SCHEMBL22187405 0.88 CA12 (0.58) CA2CA12CA1CA9MEN1
SCHEMBL29673519 0.88 CA12 (0.58) CA2CA12CA1CA9MEN1
SCHEMBL22187423 0.84 CA2 (0.56) CA2CA12CA1CA9MEN1
SCHEMBL29790378 0.84 CA2 (0.56) CA2CA12CA1CA9MEN1
SCHEMBL22187375 0.84 MEN1 (0.78) CA2CA12CA1CA9MEN1
SCHEMBL22187564 0.84 CA12 (0.70) CA2CA12CA1CA9MEN1
SCHEMBL22187256 0.84 ENPP2 (0.67) CA2CA12CA1CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 — — US disclosed
EP-4253075-B1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO LTD (JP) 2025-10-15 — — EP disclosed
US-20240190816-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO., LTD. (JP) 2024-06-13 — — US disclosed
US-20240181797-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2024-06-06 — — US disclosed
US-11945769-B2 N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same SANKO CO., LTD. (JP) 2024-04-02 — — US disclosed
EP-4313612-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD Ricoh Company, Ltd. (JP) 2024-02-07 — — EP disclosed
CN-117083182-A Thermosensitive recording layer forming liquid, thermosensitive recording medium, production method thereof, and image recording method 株式会社理光 2023-11-17 — — CN disclosed
EP-4253075-A2 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2023-10-04 — — EP disclosed
EP-3677569-A9 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2023-08-23 — — EP disclosed
WO-2022202154-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2022-09-29 — — WO disclosed
CN-111032626-B N, N' -diaryl urea derivative, process for producing the same, and thermosensitive recording material using the same 三光株式会社 2022-05-17 — — CN disclosed
US-20210340099-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO., LTD. (JP) 2021-11-04 — — US disclosed
EP-3677569-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2020-07-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11945769-B2 N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same SCN1A, SCN1B, NAAA CA2 835/4885CA12 1731/4885CA1 398/4885
US-20210340099-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SCN1A, SCN1B, NAAA CA2 805/4885CA12 1665/4885CA1 394/4885
US-20240190816-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SCN1A, SCN1B, SCN2A CA2 763/4885CA12 1565/4885CA1 343/4885
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA CA2 414/4885CA12 161/4885CA1 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.