Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19097285 | 0.99 | POLB (0.41) | POLBHTR7HTR1AHTR2APOLQ | |
| SCHEMBL17317624 | 0.88 | HTR7 (0.54) | POLBHTR7HTR1AHTR2APOLQ | |
| Hydrochloric Acid SCHEMBL19097303 | 0.86 | HTR7 (0.53) | POLBHTR7HTR1AHTR2APOLQ | |
| SCHEMBL19110592 | 0.81 | HTR7 (0.41) | HTR7HTR1AHTR2A | |
| SCHEMBL17317710 | 0.79 | GRIA2 (0.45) | POLBHTR7HTR1AHTR2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL19097284 | 0.78 | GRIA2 (0.44) | POLBHTR7HTR1AHTR2AALDH1A1 | |
| SCHEMBL17317603 | 0.78 | HTR7 (0.51) | POLBHTR7HTR1AHTR2ACYP2C9 | |
| SCHEMBL17317694 | 0.77 | POLB (0.39) | POLBHTR7HTR1AHTR2APOLQ | |
| SCHEMBL17317543 | 0.77 | HTR2C (0.53) | HTR7HTR1AHTR2AALDH1A1CYP2C9 | |
| SCHEMBL17317842 | 0.77 | GRIA2 (0.45) | HTR7HTR1AHTR2AGRIA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. | 2017-07-13 | — | — | US | disclosed |
| EP-3152206-A1 | ATX MODULATING AGENTS | Biogen MA Inc. (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015188051-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. (US) | 2015-12-10 | — | — | WO | disclosed |
| WO-2015188051-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. (US) | 2015-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | ENPP2, ATXN10, ATXN2 | POLB 4390/4885HTR7 755/4885HTR1A 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.