Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | PLEC | Q15149 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17318526 | 0.80 | POLB (0.63) | POLBNPSR1PTK2BMAPTKMT2A | |
| SCHEMBL17318537 | 0.78 | POLB (1.00) | POLBNPSR1PTK2BMAPTKMT2A | |
| SCHEMBL11528802 | 0.75 | RAB9A (1.00) | POLBNPSR1MAPTKMT2AKDM4E | |
| SCHEMBL31231560 | 0.73 | MAPT (0.85) | POLBNPSR1PTK2BMAPTKMT2A | |
| SCHEMBL6665885 | 0.72 | MEN1 (0.75) | POLBMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL6669056 | 0.72 | SMN1; SMN2 (0.75) | POLBNPSR1MAPTKMT2AKDM4E | |
| SCHEMBL7117863 | 0.72 | KDM4E (0.60) | POLBNPSR1PTK2BMAPTKMT2A | |
| SCHEMBL7124845 | 0.70 | MIF (0.70) | POLBMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23011774 | 0.70 | ALDH1A1 (0.84) | POLBNPSR1MAPTKMT2AALDH1A1 | |
| SCHEMBL17318552 | 0.70 | MAPT (0.73) | POLBNPSR1PTK2BMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015187827-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2015-12-10 | — | — | WO | disclosed |