Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MPO | P05164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16342991 | 0.85 | LMNA (0.44) | LMNAMPOHTTMAPTALDH1A1 | |
| Sulfuric Acid SCHEMBL4241603 | 0.81 | LMNA (0.41) | LMNAMPOHTTMAPTALDH1A1 | |
| SCHEMBL29954230 | 0.81 | LMNA (0.41) | LMNAHTTMAPTALDH1A1MAPK1 | |
| SCHEMBL29956741 | 0.81 | SMN1; SMN2 (0.45) | LMNAHTTMAPTALDH1A1MAPK1 | |
| SCHEMBL11487535 | 0.79 | LMNA (0.74) | LMNAMPOHTTMAPTALDH1A1 | |
| SCHEMBL15331189 | 0.72 | ALDH1A1 (0.40) | LMNAHTTMAPTALDH1A1L3MBTL1 | |
| SCHEMBL29953204 | 0.71 | ALDH1A1 (0.47) | LMNAHTTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29953708 | 0.71 | SMN1; SMN2 (0.47) | LMNAHTTMAPTALDH1A1MAPK1 | |
| SCHEMBL5928922 | 0.70 | LMNA (0.70) | LMNAHTTMAPTALDH1A1MAPK1 | |
| SCHEMBL14452375 | 0.70 | CNR1 (0.45) | MPOMAPTALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2795322-B1 | A RAPID QUANTITATIVE ASSAY TO MEASURE CFTR FUNCTION IN A PRIMARY INTESTINAL CULTURE MODEL | UMC UTRECHT HOLDING BV (NL) | 2015-12-09 | — | — | EP | disclosed |