Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14396498 | 0.93 | ALDH1A1 (0.46) | MEN1KMT2ATHRBEPHX1ALDH1A1 | |
| SCHEMBL13762975 | 0.93 | ALDH1A1 (0.46) | MEN1KMT2ATHRBEPHX1ALDH1A1 | |
| SCHEMBL14417230 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2ATHRBEPHX1ALDH1A1 | |
| SCHEMBL12203213 | 0.84 | EPHX2 (0.47) | THRBEPHX1ALDH1A1TSHR | |
| SCHEMBL14396496 | 0.84 | EPHX2 (0.47) | THRBEPHX1ALDH1A1TSHR | |
| SCHEMBL124287 | 0.79 | THRB (0.61) | THRBALDH1A1GAATSHRMAPT | |
| SCHEMBL16744077 | 0.79 | THRB (0.61) | THRBALDH1A1GAATSHRMAPT | |
| SCHEMBL13475729 | 0.78 | NAAA (0.48) | THRBEPHX1ALDH1A1HPGDTSHR | |
| SCHEMBL16425945 | 0.77 | THRB (0.47) | THRBALDH1A1TSHRMAPT | |
| SCHEMBL12642765 | 0.76 | THRB (0.53) | MEN1KMT2ATHRBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497026-B1 | POLYMERIC COMPOSITE CHIRAL STATIONARY PHASES OF BRUSH TYPE | UNIV ROMA (IT) | 2015-12-09 | — | — | EP | disclosed |