Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15970969 | 0.81 | CYP11B2 (0.46) | CYP11B1CYP11B2TSHR | |
| SCHEMBL20090804 | 0.77 | CYP11B1 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL20093956 | 0.76 | CYP11B2 (0.47) | CYP11B1CYP11B2TSHR | |
| SCHEMBL17320662 | 0.72 | CYP11B1 (0.42) | CYP11B1CYP11B2 | |
| SCHEMBL8886456 | 0.71 | FPR2 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL20093625 | 0.71 | CYP11B1 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL20588825 | 0.70 | CYP11B1 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL24411352 | 0.70 | CYP11B1 (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL3712044 | 0.69 | CYP11B1 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL1859517 | 0.67 | HTT (0.34) | CYP11B1CYP11B2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580379-B2 | Xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-02-28 | — | — | US | disclosed |
| US-20150353471-A1 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353471-A1 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | XDH, PNPO, AOX1 | CYP11B1 59/4885CYP11B2 46/4885TSHR 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.