SCHEMBL1732259

SCHEMBL1732259

Cc1cc(C)c(C(=O)P(=O)(C(=O)c2cc(C)c(C)cc2C)c2ccccc2)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CYP1A2 P05177 1/20 0.41
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 2/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
NFE2L2 Q16236 1/20 0.37
TSHR P16473 2/20 0.37
FKBP5 Q13451 1/20 0.36
USP2 O75604 1/20 0.36
ESR1 P03372 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29634650 0.86 KMT2A (0.41) KMT2ANPC1RAB9ACES2CES1
SCHEMBL1186385 0.86 KMT2A (0.41) KMT2ANPC1RAB9ACES2CES1
SCHEMBL20445720 0.84 CA2 (0.41) KMT2ANPC1RAB9ACES2CES1
SCHEMBL6548792 0.83 NFE2L2 (0.53) KMT2ANPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL8034595 0.81 HPGD (0.50) KMT2ANPC1RAB9AALDH1A1SMN1; SMN2
Lithium Ion SCHEMBL31534099 0.81 KMT2A (0.39) KMT2ANPC1RAB9ACES2CES1
SCHEMBL14342955 0.80 POLB (0.38) KMT2ANPC1RAB9ACES2CES1
SCHEMBL31246323 0.77 CYP1A2 (0.36) KMT2ANPC1RAB9ACYP1A2ALDH1A1
SCHEMBL1285564 0.77 CYP1A2 (0.36) KMT2ANPC1RAB9ACYP1A2ALDH1A1
SCHEMBL14570823 0.77 KMT2A (0.39) KMT2ANPC1RAB9ACYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114976235-B Solid polymer electrolyte and preparation method and application thereof 北京化工大学 2024-09-13 CN disclosed
US-20220372272-A1 MAGNETIC SHAPE-MEMORY POLYMERS (mSMPs) AND METHODS OF MAKING AND USING THEREOF GEORGIA TECH RESEARCH CORPORATION 2022-11-24 US disclosed
CN-114976235-A Solid polymer electrolyte and preparation method and application thereof 北京化工大学 2022-08-30 CN disclosed
US-20220133013-A1 LIGHT-CURABLE ARTIFICIAL NAILS, METHODS OF PREPARATION AND METHODS OF USE THEREOF Brilliance of Beauty, Inc. 2022-05-05 US disclosed
EP-3987181-A1 MAGNETIC SHAPE-MEMORY POLYMERS (MSMPS) AND METHODS OF MAKING AND USING THEREOF Ohio State Innovation Foundation (US) 2022-04-27 EP disclosed
US-20200237071-A1 GEL NAIL CURING DEVICE LEE KUM YONG (KR) 2020-07-30 US disclosed
US-20150072144-A1 LED CURING OF RADIATION CURABLE OPTICAL FIBER COATING COMPOSITIONS DSM IP ASSETS BV (NL) 2015-03-12 US disclosed
EP-1832913-B1 COMPOSITE CONTACT LENS AND PRODUCTION METHOD FOR SUCH A LENS HOYA CORP (JP) 2011-11-23 EP disclosed
EP-1832913-A1 COMPOSITE CONTACT LENS AND PRODUCTION METHOD FOR LENS MATERIAL HOYA CORPORATION (JP) 2007-09-12 EP disclosed
JP-2005082609-A PHOTOPOLYMERIZABLE INK COMPOSITION AND METHOD FOR DRYING THE SAME FUKUSHIMA PREFECTURE 2005-03-31 JP disclosed