SCHEMBL31246323

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1285564	1.00	CYP1A2 (0.36)	CYP1A2CA2CA4CA5ATSHR
	SCHEMBL29984769	0.86	KMT2A (0.38)	CYP1A2CA2CA4CA5ATSHR
	SCHEMBL28633825	0.86	LMNA (0.42)	TSHRSMN1; SMN2KMT2AMEN1ALDH1A1
	SCHEMBL151071	0.86	KMT2A (0.38)	CYP1A2CA2CA4CA5ATSHR
	SCHEMBL1714766	0.85	CA2 (0.39)	CYP1A2CA2CA4CA5ATSHR
	SCHEMBL1714353	0.83	CYP1A2 (0.35)	CYP1A2CA2CA4CA5ATSHR
	SCHEMBL3886065	0.83	CA2 (0.38)	CYP1A2CA2CA4CA5ATSHR
	SCHEMBL3886068	0.82	CYP1A2 (0.34)	CYP1A2CA2CA4CA5ATSHR
	Lithium Ion SCHEMBL22346192	0.82	CYP1A2 (0.34)	CYP1A2CA2CA4CA5ATSHR
	SCHEMBL28647047	0.81	LMNA (0.36)	CYP1A2TSHRSMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.